PQQ (pyrroloquinoline quinone) is one of my favorite nutrients. I’ve written and spoken about it in reference to brain health. It can be regenerated over 20,000 times to fight free radicals in the brain. PQQ is found in parsley, papaya, green bell peppers, oolong tea, green tea, eggs, and dairy.
Recent studies on worms have shown that PQQ increases their lifespans by 30%. Scientists discovered that PQQ promotes the increase of new mitochondria in aging cells. Without new mitochondria, aging cells tend to accelerate aging processes.
A test was done using human lung cells in a broth and adding inflammatory agents to test the effectiveness of PQQ in protecting cells from aging. Cells without the PQQ protection showed signs of aging brought on by TNF-alpha (tumor necrosis factor-alpha) and other cytokines (inflammation-inducing molecules).
Human lung cells not pre-treated with PQQ showed signs of aging, inflammation, and decay. Those cells pre-treated with PQQ demonstrated an ability to shun the inflammatory effects of aging and damage to their signaling pathways. PQQ demonstrated the ability to prevent cellular aging.
PQQ studies were conducted on animals with heart damage. It was remarkable that the hearts of those animals with little to no PQQ showed significant damage and overall worse outcomes compared to those protected with PQQ. The areas of heart damage were less with PQQ, cardiac function improved, blood flow improved, mitochondria function improved, and prevented heart muscle death after an ischemic attack (areas of the heart where blood flow was inadequate).
Additional animal studies were done in labs to test PQQ’s ability to improve diabetic conditions. The results with PQQ treated animals were lower blood sugar, lower lipid abnormalities, increased insulin sensitivity, reduced overall oxidative stress, and more.
Yes, these studies were done on animals. Would it not be indicative of improved mitochondrial function in humans – at least a bit? Would not similar heart, brain, bone, lung, and other human cells expect to have some level of improvement, especially in the area of cellular senescence (aging)?
I have a running battle with a fellow wellness guy who tells me that glutathione is the master antioxidant. I believe PQQ is the master antioxidant in the human body. Maybe both of us are correct. Regardless, it is a nutrient that you should not be deficient in for long-term health.
Live Longer & Enjoy Life! – Red O’Laughlin – https://RedOLaughlin.com